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CDC Launching Investigation Of Morgellons Disease

ATLANTA —

Imagine your body pocked by erupting sores. The sensation of little bugs crawling all over you. And worst of all, mysterious red and blue fibers sprouting from your skin.

It may sound like a macabre science fiction movie, but a growing legion of Americans say they suffer from this condition. And now the U.S. Centers for Disease Control and Prevention is investigating.

Some doctors dismiss these patients as delusional. But the condition -- called Morgellons -- has caused a small frenzy on the Internet, with hundreds of people pleading for help.

"Sometimes the government doesn't want to panic people until they can figure out a definitive cause," said Pat Boddie, a 62-year-old Alabama woman who said she's had Morgellons for 14 years.

"They're trying to figure out if this is going to be an epidemic. I hate to tell them, but it already is," she said.

The CDC has been receiving as many as 20 calls a day from self-diagnosed Morgellons patients. The agency has been urged to investigate by, among others, U.S. Sen. Dianne Feinstein of California.

"We're going into this with an open mind," said Dan Rutz, spokesman for a CDC Morgellons task force that began meeting in June.

But so far there is no evidence of an infectious agent, and health officials say there is not yet enough evidence even to call it a disease.

People claiming to have Morgellons report a wide variety of symptoms, ranging from joint pain to irregular bowel movements. But most describe crawling sensations along the skin, sores, fatigue, "brain fog," and the appearance of small or microscopic fibers on or under the skin.

Some say they've suffered for decades, but the syndrome did not get a name until 2002, when the name "Morgellons" (pronounced mor-GELL-uns) was chosen by Mary Leitao. The South Carolina woman, who said her son suffers from the condition, founded the Morgellons Research Foundation.

She found the name in a 1674 medical paper that described a condition called Morgellons, with symptoms somewhat like her son's. So she began using the name. "I never expected it to stick," she said.

Leitao's organization has become a leading source of information and research advocacy, but it too has become controversial.

Last week, at least three of the eight members of the organization resigned over disagreements with Leitao, the executive director, about how she's been running the foundation. One member -- the board's chairman -- sent a letter to the U.S. Internal Revenue Service, saying Leitao had failed to produce requested financial records and he voiced suspicions of financial impropriety.

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U.S. Orders Study Of Bizarre Morgellons Condition

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UNDATED —

It sounds like a freakish ailment from a horror movie: Sores erupt on your skin, mysterious threads pop out of them, and you feel like tiny bugs are crawling all over you.

Some experts believe it's a psychiatric phenomenon, yet hundreds of people say it's a true physical condition. It's called Morgellons, and now the government is about to begin its first medical study of it.

The U.S. Centers for Disease Control and Prevention is paying California-based health care giant Kaiser Permanente $338,000 to test and interview patients suffering from Morgellons' bizarre symptoms. The one-year effort will attempt to define the condition and better determine how common it is.

The study will be done in northern California, the source of many of the reports of Morgellons (pronounced mor-GELL-uns). Researchers will begin screening for patients immediately, CDC officials said Wednesday. A Kaiser official expects about 150 to 500 study participants.

Morgellons sufferers describe symptoms that include erupting sores, fatigue, the sensation of bugs crawling over them and -- perhaps worst of all -- mysterious red, blue or black fibers that sprout from their skin. They've documented their suffering on Web sites.

Some doctors believe the condition is a form of delusional parasitosis, a psychosis in which people believe they are infected with parasites.

In the study, volunteers will get blood tests and skin exams, as well as psychological evaluations, said Dr. Michele Pearson, who leads a CDC task force overseeing the study.

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Even though it sounds like science fiction, researchers are taking a second look at a controversial idea that uses futuristic ships to shoot salt water high into the sky over the oceans, creating clouds that reflect sunlight and thus counter global warming.

University of Washington atmospheric physicist Rob Wood describes a possible way to run an experiment to test the concept on a small scale in a comprehensive paper published this month in the journal Philosophical Transactions of the Royal Society.

The point of the paper – which includes updates on the latest study into what kind of ship would be best to spray the salt water into the sky, how large the water droplets should be and the potential climatological impacts – is to encourage more scientists to consider the idea of marine cloud brightening and even poke holes in it. He and a colleague detail an experiment to test the concept.

“What we’re trying to do is make the case that this is a beneficial experiment to do,” Wood said. With enough interest in cloud brightening from the scientific community, funding for an experiment may become possible, he said.

The theory behind so-called marine cloud brightening is that adding particles, in this case sea salt, to the sky over the ocean would form large, long-lived clouds. Clouds appear when water forms around particles. Since there is a limited amount of water in the air, adding more particles creates more, but smaller, droplets.

“It turns out that a greater number of smaller drops has a greater surface area, so it means the clouds reflect a greater amount of light back into space,” Wood said. That creates a cooling effect on Earth.

Marine cloud brightening is part of a broader concept known as geoengineering which encompasses efforts to use technology to manipulate the environment. Brightening, like other geoengineering proposals, is controversial for its ethical and political ramifications and the uncertainty around its impact. But those aren’t reasons not to study it, Wood said.

“I would rather that responsible scientists test the idea than groups that might have a vested interest in proving its success,” he said. The danger with private organizations experimenting with geoengineering is that “there is an assumption that it’s got to work,” he said.

Wood and his colleagues propose trying a small-scale experiment to test feasibility and begin to study effects. The test should start by deploying sprayers on a ship or barge to ensure that they can inject enough particles of the targeted size to the appropriate elevation, Wood and a colleague wrote in the report. An airplane equipped with sensors would study the physical and chemical characteristics of the particles and how they disperse.

The next step would be to use additional airplanes to study how the cloud develops and how long it remains. The final phase of the experiment would send out five to 10 ships spread out across a 100 kilometer, or 62 mile, stretch. The resulting clouds would be large enough so that scientists could use satellites to examine them and their ability to reflect light.

Wood said there is very little chance of long-term effects from such an experiment. Based on studies of pollutants, which emit particles that cause a similar reaction in clouds, scientists know that the impact of adding particles to clouds lasts only a few days.

Still, such an experiment would be unusual in the world of climate science, where scientists observe rather than actually try to change the atmosphere.

Wood notes that running the experiment would advance knowledge around how particles like pollutants impact the climate, although the main reason to do it would be to test the geoengineering idea.

A phenomenon that inspired marine cloud brightening is ship trails: clouds that form behind the paths of ships crossing the ocean, similar to the trails that airplanes leave across the sky. Ship trails form around particles released from burning fuel.

But in some cases ship trails make clouds darker. “We don’t really know why that is,” Wood said.

Despite increasing interest from scientists like Wood, there is still strong resistance to cloud brightening.

“It’s a quick-fix idea when really what we need to do is move toward a low-carbon emission economy, which is turning out to be a long process,” Wood said. “I think we ought to know about the possibilities, just in case.”

The authors of the paper are treading cautiously.

“We stress that there would be no justification for deployment of [marine cloud brightening] unless it was clearly established that no significant adverse consequences would result. There would also need to be an international agreement firmly in favor of such action,” they wrote in the paper’s summary.

There are 25 authors on the paper, including scientists from University of Leeds, University of Edinburgh and the Pacific Northwest National Laboratory. The lead author is John Latham of the National Center for Atmospheric Research and the University of Manchester, who pioneered the idea of marine cloud brightening.

Two new studies by scientists at UC Berkeley provide a clearer picture of why some species move in response to climate change, and where they go. One study, published online in the journal Global Change Biology, finds that changes in precipitation have been underappreciated as a factor in driving bird species out of their normal range.

In the other study, published the journal Proceedings of the Royal Society B, researchers found a sharp decrease in range for the Belding’s ground squirrel, but noted some surprising areas where the species found refuge.

The two studies exemplify the type of research being explored through the Berkeley Initiative in Global Change Biology, or BiGCB, an ambitious effort to better understand and predict how plants and animals will respond to changing environmental conditions by studying how they have responded to earlier periods of climate change.

The first study’s findings challenge the conventional reliance on temperature as the only climate-related force impacting where species live. The authors noted that as many as 25 percent of species have shifted in directions that were not predicted in response to temperature changes, yet few attempts have been made to investigate this.

“Our results redefine the fundamental model of how species should respond to future climate change,” said study lead author Morgan Tingley, who began the research as a graduate student in UC Berkeley’s Department of Environmental Science, Policy and Management. “We find that precipitation changes can have a major, opposing influence to temperature in a species’ range shift. Climate change may actually be tearing communities of organisms apart.”

The findings are based upon data gathered from the Grinnell Resurvey Project, which retraces the steps of Joseph Grinnell, founder of the UC Berkeley Museum of Vertebrate Zoology, in his surveys of Sierra Nevada wildlife from the early 1900s. The resurvey project, which began in 2003, was led by Craig Moritz, former UC Berkeley professor of integrative biology, and his colleagues at the Museum of Vertebrate Zoology.

For the bird study, the researchers included 99 species in 77 historic survey sites in Lassen Volcanic, Yosemite and Sequoia national parks, as well as in several national forests. In the century that has passed since the original Grinnell survey, summer and winter temperatures have increased an average of 1-2 degrees Celsius in the Sierra Nevada. Yosemite experienced the most warming – with average temperatures increasing by 3 degrees Celsius – while parts of Lassen actually got cooler and much wetter.

Among the bird species that moved upslope are the Savannah Sparrow, which shifted upward by 2,503 meters, and other meadow species such as the Red-winged Blackbird and Western Meadowlark. The ones that shifted their range downslope include both low-elevation species like the Ash-throated Flycatcher and Western Scrub-Jay, and high-elevation species like the Cassin’s Finch and Red-breasted Nuthatch.

“Temperature did not explain the majority of these shifts,” said Tingley, who is now a postdoctoral researcher at Princeton University’s Program in Science, Technology and Environmental Policy. “Only when we included precipitation as an explanatory variable did our models adequately explain the movement patterns we observed.”

The researchers found that while rising temperatures tended to push birds to cooler regions upslope, increased precipitation, which is more common at higher elevations, pulled them downslope.

“We believe many species may feel this divergent pressure from temperature and precipitation, and in the end, only one wins,” said Tingley.

Notably, more than half of the bird species in each of the three study regions did not shift their range despite pressures from climate change. “Moving is a sign of adaptation, which is good from a conservation standpoint,” said Tingley.

“More worrisome are the species that have not shifted. How are they adapting? Are they moving, but we just can’t detect it? Or are they slowly declining as environmental conditions gradually become less ideal where they live?”

The answers are complex, as illustrated by the second UC Berkeley paper about range changes for a species of squirrel found in the mountains of the western United States.

In that paper, researchers again used information obtained from the Grinnell Resurvey Project. Through visual observations and trapping surveys conducted throughout the mountains of California, they discovered that the Belding’s ground squirrel had disappeared from 42 percent of the sites where they were recorded in the early 1900s. Extinctions were particularly common at sites with high average winter temperatures and large increases in precipitation over the last century.

“We were surprised to see such a dramatic decline in this species, which is well-known to Sierran hikers and was thought to be fairly common,” said study lead author Toni Lyn Morelli, a former National Science Foundation postdoctoral researcher who was based at UC Berkeley. “In fact, the rate of decline is much greater than that seen in the same region for the pika, a small mountain-dwelling cousin of the rabbit that has become the poster child for the effects of climate warming in the contiguous United States.”

Morelli added that the squirrels are thriving in areas that have been modified by humans. For example, irrigated Mono Lake County Park serves as an artificial oasis that sustains squirrel populations despite otherwise hot and dry conditions in eastern California.

“As predictions indicate that the range of the Belding’s ground squirrel could disappear out of California by the end of the century, these areas might be particularly important for this and other climate-impacted species,” said Morelli, who is now a technical advisor for the U.S. Forest Service’s International Programs in the Democratic Republic of Congo.

Although the Belding’s ground squirrel is widespread, the rapid decline in its distribution is of concern because it is an important source of food for raptors and carnivores. However, the paper suggests that even when climate change causes large range declines, some species can persist in human-modified areas.

“Taken together, these two studies indicate that many species have been responding to recent climate change, yet the complexities of a species’ ecological needs and their responses to habitat modification by humans can result in unanticipated responses,” said Steven Beissinger, professor at UC Berkeley’s Department of Environmental Science, Policy and Management and the senior author on both studies. “This makes it very challenging for scientists to project how species will respond to future climate change.”

Funding from the National Science Foundation, National Park Service, and California Landscape Conservation Cooperative helped support this research.